RepurposeX
Live data: Open Targets · ChEMBL · DGIdb · ClinicalTrials.gov · PubMed

Could a drug we already have
help with this disease?

Drug repurposing, made searchable. We search the world's largest open medical and bio databases, surface drugs that share biological pathways with diseases they weren't built for, and explain the science in plain English. Not medical advice, just a starting point for smarter research.

Try a disease name like "Alzheimer", a drug name, or a gene. Press Enter to open.
True stories

Drugs that ended up treating something else

Six drugs you've heard of, each invented for one thing and now used for something completely different. The pattern this site looks for.

Ozempic
semaglutide
Made for
Type 2 diabetes
but now
Now also for
Weight loss
Scale today
~$30B/yr globally

A diabetes injection that turned out to dramatically reduce appetite. Sold as Ozempic for diabetes and Wegovy for weight loss — together they're on pace to be among the largest pharmaceutical products ever sold.

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Viagra
sildenafil
Made for
Chest pain (angina)
but now
Now also for
Erectile dysfunction
Scale today
$2B+/yr at peak

First tested as a heart medicine for chest pain. It didn't help with chest pain — but male volunteers in the trials reported a side effect they wanted to keep. Pfizer pivoted, and the rest is famous.

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Botox
onabotulinumtoxinA
Made for
Crossed eyes
but now
Now also for
Wrinkles + migraines
Scale today
~$5B/yr globally

First approved in 1989 to treat crossed eyes and eyelid spasms. Doctors noticed it also smoothed forehead wrinkles. Today it treats chronic migraines, excessive sweating, and overactive bladder — alongside its famous cosmetic use.

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Wellbutrin / Zyban
bupropion
Made for
Depression
but now
Now also for
Quitting smoking
Scale today
Top-prescribed quit-smoking aid

Patients on this antidepressant noticed cigarettes felt less satisfying. The same exact molecule was repackaged as Zyban — and became one of the most-prescribed prescription aids for quitting smoking.

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Aspirin
acetylsalicylic acid
Made for
Pain and fever
but now
Now also for
Preventing heart attacks
Scale today
~100B+ doses/yr worldwide

A 1900s headache pill. In low daily doses, it thins the blood just enough to lower the chance of clots — making the world's oldest drug a standard tool for preventing a second heart attack or stroke in adults who've already had one.

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Rogaine (minoxidil)
minoxidil
Made for
Severe high blood pressure
but now
Now also for
Hair loss
Scale today
~$1B/yr in haircare

An oral blood-pressure medicine with one famously inconvenient side effect: patients grew hair everywhere. Researchers reformulated it into a topical foam, and a multi-billion-dollar hair-restoration market was born.

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